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Non-Inferiority Trials: Understanding the Concepts - Tutorials and FundamentalsNon-Inferiority Trials: Understanding the Concepts - Tutorials and FundamentalsNon-Inferiority Trials: Understanding the Concepts - Tutorials and FundamentalsNon-Inferiority Trials: Understanding the Concepts - Tutorials and FundamentalsUnderstanding the vortex of non-inferiority trials — NephJCUnderstanding the vortex of non-inferiority trials — NephJCNon-Inferiority Trials: Understanding the Concepts - Tutorials and FundamentalsNon-Inferiority Trials: Understanding the Concepts - Tutorials and FundamentalsNon-Inferiority Trials: Understanding the Concepts - Tutorials and FundamentalsNon-Inferiority Trials: Understanding the Concepts - Tutorials and FundamentalsNon-Inferiority Trials: Understanding the Concepts - Tutorials and FundamentalsNon-Inferiority Trials: Understanding the Concepts - Tutorials and FundamentalsNon-inferiority versus superiority trial design for new antibiotics in an era of high antimicrobial resistance: the case for post-marketing, adaptive randomised controlled trials - The Lancet Infectious DiseasesNon-inferiority versus superiority trial design for new antibiotics in an era of high antimicrobial resistance: the case for post-marketing, adaptive randomised controlled trials - The Lancet Infectious DiseasesNon-inferiority cancer clinical trials: scope and purposes underlying their design - Annals of OncologyNon-inferiority cancer clinical trials: scope and purposes underlying their design - Annals of OncologyNon-inferiority trials: design concepts and issues - the encounters of academic consultants in statisticsNon-inferiority trials: design concepts and issues - the encounters of academic consultants in statisticsDemonstrating equivalence and non‐inferiority of medical education concepts - Klasen - 2021 - Medical Education - Wiley Online LibraryDemonstrating equivalence and non‐inferiority of medical education concepts - Klasen - 2021 - Medical Education - Wiley Online LibraryTesting for non-inferior mortality: a systematic review of non-inferiority margin sizes and trial characteristics | BMJ OpenTesting for non-inferior mortality: a systematic review of non-inferiority margin sizes and trial characteristics | BMJ OpenNon-inferiority clinical trials: concepts and issuesNon-inferiority clinical trials: concepts and issuesMeta-analysis of noninferiority and equivalence trials: ignoring trial design leads to differing and possibly misleading conclusions - Journal of Clinical EpidemiologyMeta-analysis of noninferiority and equivalence trials: ignoring trial design leads to differing and possibly misleading conclusions - Journal of Clinical EpidemiologyStatistical methods for non-adherence in non-inferiority trials: useful and used? A systematic review | BMJ OpenStatistical methods for non-adherence in non-inferiority trials: useful and used? A systematic review | BMJ OpenDesigning noninferiority tuberculosis treatment trials: Identifying practical advantages for drug regimens with acceptable effectiveness | PLOS MedicineDesigning noninferiority tuberculosis treatment trials: Identifying practical advantages for drug regimens with acceptable effectiveness | PLOS MedicineWhy restricted mean survival time methods are especially useful for non-inferiority trials - Matteo Quartagno, Tim P Morris, Ian R White, 2021Why restricted mean survival time methods are especially useful for non-inferiority trials - Matteo Quartagno, Tim P Morris, Ian R White, 2021Testing for non-inferior mortality: a systematic review of non-inferiority margin sizes and trial characteristics | BMJ OpenTesting for non-inferior mortality: a systematic review of non-inferiority margin sizes and trial characteristics | BMJ OpenFeasibility and economic assessment of chromocolonoscopy for detection of proximal serrated neoplasia within a population-based colorectal cancer screening programme (CONSCOP): an open-label, randomised controlled non-inferiority trial - The Lancet ...Feasibility and economic assessment of chromocolonoscopy for detection of proximal serrated neoplasia within a population-based colorectal cancer screening programme (CONSCOP): an open-label, randomised controlled non-inferiority trial - The Lancet ...Phase 0/microdosing approaches: time for mainstream application in drug development? | Nature Reviews Drug DiscoveryPhase 0/microdosing approaches: time for mainstream application in drug development? | Nature Reviews Drug DiscoveryClinical research study designs: The essentials - Chidambaram - 2019 - Pediatric Investigation - Wiley Online LibraryClinical research study designs: The essentials - Chidambaram - 2019 - Pediatric Investigation - Wiley Online LibraryResponse-adapted omission of radiotherapy and comparison of consolidation chemotherapy in children and adolescents with intermediate-stage and advanced-stage classical Hodgkin lymphoma (EuroNet-PHL-C1): a titration study with an open-label, embedded ...Response-adapted omission of radiotherapy and comparison of consolidation chemotherapy in children and adolescents with intermediate-stage and advanced-stage classical Hodgkin lymphoma (EuroNet-PHL-C1): a titration study with an open-label, embedded ...Perioperative or postoperative adjuvant oxaliplatin with S-1 versus adjuvant oxaliplatin with capecitabine in patients with locally advanced gastric or gastro-oesophageal junction adenocarcinoma undergoing D2 gastrectomy (RESOLVE): an open-label ...Perioperative or postoperative adjuvant oxaliplatin with S-1 versus adjuvant oxaliplatin with capecitabine in patients with locally advanced gastric or gastro-oesophageal junction adenocarcinoma undergoing D2 gastrectomy (RESOLVE): an open-label ...Efficacy and safety of dolutegravir or darunavir in combination with lamivudine plus either zidovudine or tenofovir for second-line treatment of HIV infection (NADIA): week 96 results from a prospective, multicentre, open-label, factorial,Efficacy and safety of dolutegravir or darunavir in combination with lamivudine plus either zidovudine or tenofovir for second-line treatment of HIV infection (NADIA): week 96 results from a prospective, multicentre, open-label, factorial,Transforming clinical trials in rheumatology: towards patient-centric precision medicine | Nature Reviews RheumatologyTransforming clinical trials in rheumatology: towards patient-centric precision medicine | Nature Reviews RheumatologyFrontiers | A Counseling Application as an Alternative Tool in Increasing Coping Self-Efficacy Among University Students With Academic Distress During Coronavirus Disease 2019 Pandemic in Indonesia: A Study Protocol for a RandomizedFrontiers | A Counseling Application as an Alternative Tool in Increasing Coping Self-Efficacy Among University Students With Academic Distress During Coronavirus Disease 2019 Pandemic in Indonesia: A Study Protocol for a RandomizedSafety and immunogenicity of heterologous versus homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine (Com-COV): a single-blind, randomised, non-inferiority trial - The LancetSafety and immunogenicity of heterologous versus homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine (Com-COV): a single-blind, randomised, non-inferiority trial - The LancetA multi-national, randomised, open-label, parallel, phase III non- inferiority study comparing NK105 and paclitaxel in metastatic or recurrent breast cancer patients | British Journal of CancerA multi-national, randomised, open-label, parallel, phase III non- inferiority study comparing NK105 and paclitaxel in metastatic or recurrent breast cancer patients | British Journal of CancerJCM | Free Full-Text | Strategies to Improve Participation of Older Adults in Cancer Research | HTMLJCM | Free Full-Text | Strategies to Improve Participation of Older Adults in Cancer Research | HTMLOperational Challenges for Biosimilar StudiesOperational Challenges for Biosimilar StudiesFrontiers | Neoadjuvant Chemoradiotherapy and Surgery for Esophageal Squamous Cell Carcinoma Versus Definitive Chemoradiotherapy With Salvage Surgery as Needed: The Study Protocol for the Randomized Controlled NEEDS TrialFrontiers | Neoadjuvant Chemoradiotherapy and Surgery for Esophageal Squamous Cell Carcinoma Versus Definitive Chemoradiotherapy With Salvage Surgery as Needed: The Study Protocol for the Randomized Controlled NEEDS TrialDesign and Sample Size for Vaccine Trials | Case Study of Covid-19Design and Sample Size for Vaccine Trials | Case Study of Covid-19Liquid biopsy enters the clinic — implementation issues and future challenges | Nature Reviews Clinical OncologyLiquid biopsy enters the clinic — implementation issues and future challenges | Nature Reviews Clinical OncologyEfficacy and Safety of Daprodustat Compared with Darbepoetin Alfa in Japanese Hemodialysis Patients with Anemia | American Society of NephrologyEfficacy and Safety of Daprodustat Compared with Darbepoetin Alfa in Japanese Hemodialysis Patients with Anemia | American Society of NephrologyPDF) Evaluating “Superiority”, “Equivalence” and “Non-Inferiority” in Clinical TrialsPDF) Evaluating “Superiority”, “Equivalence” and “Non-Inferiority” in Clinical TrialsNIA-Funded Active Alzheimer's and Related Dementias Clinical Trials and Studies | National Institute on AgingNIA-Funded Active Alzheimer's and Related Dementias Clinical Trials and Studies | National Institute on AgingCore Concepts - Evaluation and Management of Virologic Failure - Antiretroviral Therapy - National HIV CurriculumCore Concepts - Evaluation and Management of Virologic Failure - Antiretroviral Therapy - National HIV CurriculumEfficacy, safety, and lot-to-lot immunogenicity of an inactivated SARS-CoV-2 vaccine (BBV152): interim results of a randomised, double-blind, controlled, phase 3 trial - The LancetEfficacy, safety, and lot-to-lot immunogenicity of an inactivated SARS-CoV-2 vaccine (BBV152): interim results of a randomised, double-blind, controlled, phase 3 trial - The LancetNIA-Funded Active Alzheimer's and Related Dementias Clinical Trials and Studies | National Institute on AgingNIA-Funded Active Alzheimer's and Related Dementias Clinical Trials and Studies | National Institute on AgingBiomedicines | Free Full-Text | Emerging Evidence and Treatment Perspectives from Randomized Clinical Trials in Systemic Sclerosis: Focus on Interstitial Lung Disease | HTMLBiomedicines | Free Full-Text | Emerging Evidence and Treatment Perspectives from Randomized Clinical Trials in Systemic Sclerosis: Focus on Interstitial Lung Disease | HTMLDesign and Interpretation of Clinical Trials | CourseraDesign and Interpretation of Clinical Trials | CourseraScientific method - WikipediaScientific method - WikipediaAssociation between tocilizumab, sarilumab and all-cause mortality at 28 days in hospitalised patients with COVID-19: A network meta-analysis | PLOS ONEAssociation between tocilizumab, sarilumab and all-cause mortality at 28 days in hospitalised patients with COVID-19: A network meta-analysis | PLOS ONESafety and efficacy of erenumab in patients with trigeminal neuralgia in Denmark: a double-blind, randomised, placebo-controlled, proof-of-concept study - The Lancet NeurologySafety and efficacy of erenumab in patients with trigeminal neuralgia in Denmark: a double-blind, randomised, placebo-controlled, proof-of-concept study - The Lancet NeurologyUse of Race in Clinical Diagnosis and Decision Making: Overview and Implications | KFFUse of Race in Clinical Diagnosis and Decision Making: Overview and Implications | KFFTranslating evidence into practice: eligibility criteria fail to eliminate clinically significant differences between real-world and study populations | npj Digital MedicineTranslating evidence into practice: eligibility criteria fail to eliminate clinically significant differences between real-world and study populations | npj Digital MedicineScreening PLHIV for depression using PHQs: A RCT comparing non-selective with selective screening strategy within a primary health care facility in Uganda | PLOS ONEScreening PLHIV for depression using PHQs: A RCT comparing non-selective with selective screening strategy within a primary health care facility in Uganda | PLOS ONEComparison of prostatic artery embolisation (PAE) versus transurethral resection of the prostate (TURP) for benign prostatic hyperplasia: randomised, open label, non-inferiority trial | The BMJComparison of prostatic artery embolisation (PAE) versus transurethral resection of the prostate (TURP) for benign prostatic hyperplasia: randomised, open label, non-inferiority trial | The BMJImproving clinical trial outcomes in amyotrophic lateral sclerosis | Nature Reviews NeurologyImproving clinical trial outcomes in amyotrophic lateral sclerosis | Nature Reviews NeurologyInequality in science and the case for a new agenda | PNASInequality in science and the case for a new agenda | PNASCancers | Free Full-Text | Exploring Essential Issues for Improving Therapeutic Cancer Vaccine Trial Design | HTMLCancers | Free Full-Text | Exploring Essential Issues for Improving Therapeutic Cancer Vaccine Trial Design | HTMLMultiplicity – What is it, and why is it important? - Quantics BiostatisticsMultiplicity – What is it, and why is it important? - Quantics BiostatisticsFrontiers | Review: Lessons Learned From Clinical Trials Using Antimicrobial Peptides (AMPs)Frontiers | Review: Lessons Learned From Clinical Trials Using Antimicrobial Peptides (AMPs)Prophylactic hydration to protect renal function from intravascular iodinated contrast material in patients at high risk of contrast-induced nephropathy (AMACING): a prospective, randomised, phase 3, controlled, open-label, non-inferiority trial - The ...Prophylactic hydration to protect renal function from intravascular iodinated contrast material in patients at high risk of contrast-induced nephropathy (AMACING): a prospective, randomised, phase 3, controlled, open-label, non-inferiority trial - The ...Peer video feedback builds basic life support skills: A randomized controlled non-inferiority trial | PLOS ONEPeer video feedback builds basic life support skills: A randomized controlled non-inferiority trial | PLOS ONEExercise under heat stress: thermoregulation, hydration, performance implications, and mitigation strategies | Physiological ReviewsExercise under heat stress: thermoregulation, hydration, performance implications, and mitigation strategies | Physiological ReviewsEffects of Intermittent Fasting on Health, Aging, and Disease | NEJMEffects of Intermittent Fasting on Health, Aging, and Disease | NEJMDiversity, Equity and Inclusion: Key Terms and DefinitionsDiversity, Equity and Inclusion: Key Terms and DefinitionsFrontiers | Strategies to Circumvent the Side-Effects of Immunotherapy Using Allogeneic CAR-T Cells and Boost Its Efficacy: Results of Recent Clinical TrialsFrontiers | Strategies to Circumvent the Side-Effects of Immunotherapy Using Allogeneic CAR-T Cells and Boost Its Efficacy: Results of Recent Clinical TrialsSafety of a Restrictive versus Liberal Approach to Red Blood Cell Transfusion on the Outcome of AKI in Patients Undergoing Cardiac Surgery: A Randomized Clinical Trial | American Society of NephrologySafety of a Restrictive versus Liberal Approach to Red Blood Cell Transfusion on the Outcome of AKI in Patients Undergoing Cardiac Surgery: A Randomized Clinical Trial | American Society of NephrologyCluster Randomized Trials: Concepts - Tutorials and FundamentalsCluster Randomized Trials: Concepts - Tutorials and FundamentalsIndividualised versus standard duration of elastic compression therapy for prevention of post-thrombotic syndrome (IDEAL DVT): a multicentre, randomised, single-blind, allocation-concealed, non-inferiority trial - The Lancet HaematologyIndividualised versus standard duration of elastic compression therapy for prevention of post-thrombotic syndrome (IDEAL DVT): a multicentre, randomised, single-blind, allocation-concealed, non-inferiority trial - The Lancet HaematologyInstructional Design in Medical Education [Incl. Seminar] | Lecturio MedicalInstructional Design in Medical Education [Incl. Seminar] | Lecturio MedicalIn silico clinical trials for pediatric orphan diseases | Scientific ReportsIn silico clinical trials for pediatric orphan diseases | Scientific ReportsCancer survival statistics for patients and healthcare professionals – a tutorial of real‐world data analysis - Eloranta - 2021 - Journal of Internal Medicine - Wiley Online LibraryCancer survival statistics for patients and healthcare professionals – a tutorial of real‐world data analysis - Eloranta - 2021 - Journal of Internal Medicine - Wiley Online LibraryUX Gamification: Concepts For increasing User EngagementUX Gamification: Concepts For increasing User EngagementFrontiers | Asymmetry and Heterogeneity: Part and Parcel in Cardiac Autonomic Innervation and FunctionFrontiers | Asymmetry and Heterogeneity: Part and Parcel in Cardiac Autonomic Innervation and FunctionTiming of Androgen Deprivation Treatment for Men with Biochemical Recurrent Prostate Cancer in the Context of Novel Therapies | Journal of UrologyTiming of Androgen Deprivation Treatment for Men with Biochemical Recurrent Prostate Cancer in the Context of Novel Therapies | Journal of UrologyNuclear Medicine and Artificial Intelligence: Best Practices for Algorithm Development | Journal of Nuclear MedicineNuclear Medicine and Artificial Intelligence: Best Practices for Algorithm Development | Journal of Nuclear MedicineHarnessing data science to advance radiation oncology - Vogelius - 2020 - Molecular Oncology - Wiley Online LibraryHarnessing data science to advance radiation oncology - Vogelius - 2020 - Molecular Oncology - Wiley Online LibraryFrontiers | Evidence-Based Updates to Thrombectomy: Targets, New Techniques, and DevicesFrontiers | Evidence-Based Updates to Thrombectomy: Targets, New Techniques, and DevicesFrontiers | What Is New in the Anti–Pseudomonas aeruginosa Clinical Development Pipeline Since the 2017 WHO Alert?Frontiers | What Is New in the Anti–Pseudomonas aeruginosa Clinical Development Pipeline Since the 2017 WHO Alert?Modelling brain representations of abstract concepts | PLOS Computational BiologyModelling brain representations of abstract concepts | PLOS Computational BiologyTargeting HER2-positive breast cancer: advances and future directions | Nature Reviews Drug DiscoveryTargeting HER2-positive breast cancer: advances and future directions | Nature Reviews Drug DiscoveryBiomedicines | Free Full-Text | 177Lu-PSMA Radioligand Therapy Is Favorable as Third-Line Treatment of Patients with Metastatic Castration-Resistant Prostate Cancer. A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials | HTMLBiomedicines | Free Full-Text | 177Lu-PSMA Radioligand Therapy Is Favorable as Third-Line Treatment of Patients with Metastatic Castration-Resistant Prostate Cancer. A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials | HTMLNeuronal population dynamics during motor plan cancellation in nonhuman primates | PNASNeuronal population dynamics during motor plan cancellation in nonhuman primates | PNASChallenges to nutrition management among patients using antiretroviral therapy in primary health 'centres' in Addis Ababa, Ethiopia: A phenomenological study | PLOS ONEChallenges to nutrition management among patients using antiretroviral therapy in primary health 'centres' in Addis Ababa, Ethiopia: A phenomenological study | PLOS ONENovel Agents in the Management of Hepatic Encephalopathy: A ReviewNovel Agents in the Management of Hepatic Encephalopathy: A ReviewIntervention StudiesIntervention StudiesCureus | Diagnosis and Management of an Inferior ST-elevation Myocardial Infarction: A Simulation ScenarioCureus | Diagnosis and Management of an Inferior ST-elevation Myocardial Infarction: A Simulation ScenarioUnderstanding and overcoming adverse consequences of genome editing on hematopoietic stem and progenitor cells: Molecular TherapyUnderstanding and overcoming adverse consequences of genome editing on hematopoietic stem and progenitor cells: Molecular TherapyPGM-Free Oxygen-Reduction Catalyst Development for Proton-Exchange Membrane Fuel Cells: Challenges, Solutions, and Promises | Accounts of Materials ResearchPGM-Free Oxygen-Reduction Catalyst Development for Proton-Exchange Membrane Fuel Cells: Challenges, Solutions, and Promises | Accounts of Materials ResearchFrontiers | A biologically oriented algorithm for spatial sound segregationFrontiers | A biologically oriented algorithm for spatial sound segregationThe MoveStrong program for promoting balance and functional strength training and adequate protein intake in pre-frail older adults: A pilot randomized controlled trial | PLOS ONEThe MoveStrong program for promoting balance and functional strength training and adequate protein intake in pre-frail older adults: A pilot randomized controlled trial | PLOS ONECureus | Multiplatform Radiosurgery for Intracranial Meningiomas and Dose to the Dural TailCureus | Multiplatform Radiosurgery for Intracranial Meningiomas and Dose to the Dural TailNuclear Medicine and Artificial Intelligence: Best Practices for Algorithm Development | Journal of Nuclear MedicineNuclear Medicine and Artificial Intelligence: Best Practices for Algorithm Development | Journal of Nuclear MedicineTrial Design and Endpoints in Hepatocellular Carcinoma: AASLD Consensus Conference - Llovet - 2021 - Hepatology - Wiley Online LibraryTrial Design and Endpoints in Hepatocellular Carcinoma: AASLD Consensus Conference - Llovet - 2021 - Hepatology - Wiley Online LibraryNeonatal Research | Following important research in neonatology / newborn medicine from around the worldNeonatal Research | Following important research in neonatology / newborn medicine from around the worldOcular Drug Delivery: Present Innovations and Future Challenges | Journal of Pharmacology and Experimental TherapeuticsOcular Drug Delivery: Present Innovations and Future Challenges | Journal of Pharmacology and Experimental TherapeuticsOn the Journey Toward Health Equity: Data, Culture Change, and the First Step | NEJM CatalystOn the Journey Toward Health Equity: Data, Culture Change, and the First Step | NEJM CatalystFrontiers | Transition From Sublexical to Lexico-Semantic Stimulus ProcessingFrontiers | Transition From Sublexical to Lexico-Semantic Stimulus ProcessingMolecular Hybridization-Inspired Optimization of Diarylbenzopyrimidines as HIV-1 Nonnucleoside Reverse Transcriptase Inhibitors with Improved Activity against K103N and E138K Mutants and Pharmacokinetic Profiles | ACS Infectious DiseasesMolecular Hybridization-Inspired Optimization of Diarylbenzopyrimidines as HIV-1 Nonnucleoside Reverse Transcriptase Inhibitors with Improved Activity against K103N and E138K Mutants and Pharmacokinetic Profiles | ACS Infectious DiseasesInhaled Medicines: Past, Present, and Future | Pharmacological ReviewsInhaled Medicines: Past, Present, and Future | Pharmacological ReviewsLysosomal inhibition sensitizes TMEM16A-expressing cancer cells to chemotherapy | PNASLysosomal inhibition sensitizes TMEM16A-expressing cancer cells to chemotherapy | PNASMapping Pediatric Oncology Clinical Trial Collaborative Groups on the Global Stage | JCO Global OncologyMapping Pediatric Oncology Clinical Trial Collaborative Groups on the Global Stage | JCO Global OncologyMedicina | Free Full-Text | Ultrasound Elastography—Cornerstone of Non-Invasive Metabolic Dysfunction-Associated Fatty Liver Disease Assessment | HTMLMedicina | Free Full-Text | Ultrasound Elastography—Cornerstone of Non-Invasive Metabolic Dysfunction-Associated Fatty Liver Disease Assessment | HTMLFrontiers | Can Broadly Neutralizing HIV-1 Antibodies Help Achieve an ART-Free Remission?Frontiers | Can Broadly Neutralizing HIV-1 Antibodies Help Achieve an ART-Free Remission?Treatment with an Anti-CK2 Synthetic Peptide Improves Clinical Response in COVID-19 Patients with Pneumonia. A Randomized and Controlled Clinical Trial | ACS Pharmacology & Translational ScienceTreatment with an Anti-CK2 Synthetic Peptide Improves Clinical Response in COVID-19 Patients with Pneumonia. A Randomized and Controlled Clinical Trial | ACS Pharmacology & Translational ScienceUnderstanding the vortex of non-inferiority trials — NephJCUnderstanding the vortex of non-inferiority trials — NephJCTirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes | NEJMTirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes | NEJMIn a 14:1 vote, ODAC nixes a PD-1 drug developed in China; data not generalizable to U.S. population - The Cancer LetterIn a 14:1 vote, ODAC nixes a PD-1 drug developed in China; data not generalizable to U.S. population - The Cancer Letter